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News: Bacterial ‘Nanosyringe’ Could Deliver Gene Therapy to Human Cells

This novel injection system could help advance gene therapy by nimbly inserting gene-editing enzymes into a variety of cell types. Inside the gut of a caterpillar lives a worm, and inside the worm lurks a bioluminescent bacterium named Photorhabdus asymbiotica, which makes the caterpillar glow in the dark. But this nesting-doll-like setup has another, more harmful effect: the bacteria secrete a deadly molecular syringe, 100 nanometers long, that latches onto the insect’s cells. Once attached to a cell, the syringe pushes a molecular spear through the cell’s membrane that releases a toxic payload. As its insect host dies and decomposes, the bacteria escape to colonize their next victim. 

Read more…

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Conference: Novel Cell Line Engineering & Development Summit

The inaugural Novel Cell Line Engineering & Development Summit (May 10-11, 2023) is the only ATMP-focused, forward-facing meeting dedicated to overcoming the current challenges in cell line development and engineering. Optimizing pioneering cell lines to increase stability, scalability, and productivity will enable you and your organization to increase efficiency, reduce the cost of goods, and most importantly, accelerate patient access!

Join expert speakers from Sanofi, AstraZeneca, Vedere Bio II, Versatope Therapeutics, Takeda, and many more industry leaders as they navigate their strategies in 2023 to enhance cell line engineering and development approaches. 

With 60+ leaders expected in the room, 3 conference days, and 20+ actionable case studies, this is not a summit to miss out on!

Register now…

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Conference: 2nd Cell Therapy Potency Assay Summit

Looking to revolutionize your cell therapy potency assay this year?
Having difficulty defining what optimal potency looks like?
Determined to translate the precise mechanisms of action into the assay?
Striving for a smooth pathway to regulatory approval?

Register your place today for the 2nd Cell Therapy Potency Assay Summit (May 31 - June 2, 2023), dedicated to addressing the unique challenges the potency assay poses to the cell therapy field.

Register now…

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Conference: Gene Therapy for Neurological Disorders Summit Europe 

Returning as the pinnacle event in the industry, the 4th Annual Gene Therapy for Neurological Disorders Summit Europe (6-8 June 2023, Amsterdam) enables you to bring your gene therapy to patients in Europe. This year’s content takes a greater focus on:

  • Innovation in preclinical models and vector technology
  • Showcasing novel approaches to improve delivery in a safe manner
  • Optimizing administration route to reduce the patient
  • Understanding what needs to be done to crack the European market

Covering both neurodevelopmental and neurodegenerative disorders, join 80+ of your peers in Amsterdam this June. We’ll be welcoming those leading biopharma and academia, working in preclinical, clinical and market access to help get safer, more efficacious gene therapies for neurological disorders to market in Europe.


As the gene therapy community gets a second wind and as the clinical promise in neurology begins to be realised, now is the time to get your hands on the latest innovations in this field to bring safe, efficacious and commercially successful products to market in Europe.

Register now…

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Conference: Gene Therapy CMC & Analytics

Increasing manufacturing efficiency and reducing impurities is crucial to maximise the quality and production of gene therapeutics. From regulatory updates to novel analytical tools and technologies, join the conversation tackling the major challenges effecting the production of gene therapies. 

Gene Therapy CMC & Analytics (June 7-8, 2023) brings together the main players of the gene therapy space, through inspiring keynote presentations and engaging panel discussions, to discuss the latest challenges and advances in analytics and manufacturing strategies to improve gene therapy products.

Hear from the likes of the FDA, Sangamo Therapeutics, DPS Group, Biogen, BioMarin, National Institute of Biology, Alnylam Pharmaceuticals, and many more.

Register now…

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Conference: 3rd Gene Therapy Patient Engagement Summit

The role of patient engagement in gene therapy development is changing.


As the global healthcare system accelerates its acceptance of gene therapies as one-time, potentially curative, treatment options for rare diseases, the role of patient engagement in informing drug development strategy is evolving.


At this interface lies the 3rd Gene Therapy Patient Engagement Summit (June 13-15, 2023), uniting patient advocacy and engagement experts from leading gene therapy and gene editing drug developers, along with patient groups and patients themselves. Talks, workshops, and group discussions will shed a light on how to better integrate the patient voice into gene therapy programs at crucial stages of the drug development process.
Join us in Boston this summer to gain the actionable insights, tools, and strategies you need to better implement patient input into patient-centric gene therapy programs.

Register now…

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Conference: 3rd Gene and Cell Therapies: CMC, CGT & Vector Manufacturing Summit

Join the leading practitioners and consultants at the 3rd Gene and Cell Therapies: CMC, CGT & Vector Manufacturing Summit. (20-21 June 2023)

The gene and cell therapies clinical impact, production and processes efficiency hardly depend on the unique challenges, related to CMC, analytical, process development, automation, manufacturing, facility design, aseptic processing, supply chain and other, developers of gene and cell therapies must resolve. Get answers to your burning questions, explore new technologies, and extend partnerships.

Register now…

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Conference: 6th Aseptic Processing Summit

Join the leading practitioners and consultants at the 6th Aseptic Processing Summit. (21-22 June 2023). The gene and cell therapies clinical impact, production and processes efficiency hardly depend on the unique challenges, related to CMC, analytical, process development, automation, manufacturing, facility design, aseptic processing, supply chain and other, developers of gene and cell therapies must resolve. Get answers to your burning questions, explore new technologies, and extend partnerships.

Register now…

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Conference: Gene Therapy & Rare Diseases 

Join us at GT+R 2023 (June 26-29, 2023), the premier event for gene therapy and rare disease therapeutics! Experience first-hand insights from the most seasoned experts in the field and meet thought leaders, advocates, researchers, and industry executives driving the future of these fields. Don't miss this opportunity to stay ahead of the game and shape the future of gene therapy and rare disease innovation.

Register now…

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Conference: Next Generation Gene Therapy Vectors Summit 

As the biggest industry-led meeting on novel vector development, the 3rd Annual Next Generation Gene Therapy Vectors Summit (June 27-29, 2023 | Boston, MA) will bring together 100+ key opinion leaders to help solve the safety, efficiency, and scalability challenges of the next generation of vectors.

Industry heavyweights such as Novartis, Spark Therapeutics, Capsida Biotherapeutics, and Dyno Therapeutics will deliver data-led seminars, workshops, and panels to aid in the progression of promising vector designs from discovery to clinical trials.

Uniting industry pioneers such as Dave Chu (Capsida Biotherapeutics), Sean Armour (Spark Therapeutics), Eric Kelsic (Dyno Therapeutics), Jing Liao (Alexion Pharmaceuticals), and others – this summit will be your ultimate roadmap to the future of the industry as it upgrades to the next generation of vectors.

Register now…

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Upcoming conferences and meetings

  • 17 - 19 April 2023 - 2nd LNP Formulation & Process Development Summit 2023 - Gene Therapy delivery - Boston
  • 18 - 20 April 2023 - mRNA Process Development & Manufacturing Summit Europe - Frankfurt, Germany
  • 18 - 20 April 2023 - Cell & Gene Therapy Manufacturing & Commercialization Asia - Online event
  • 24 - 25 April 2023 - The Economist's Cell & Gene Therapy summit - Brussels, Belgium
  • 25 - 27 April 2023 - Gene Therapy Durability Summit - Boston, MA
  • 25 - 27 April 2023 - Next Generation Cardiovascular Drug Development Summit - Boston, MA
  • 26 - 27 April 2023 - World Oncology Cell Therapy Congress USA - Boston, MA
  • 26 - 27 April 2023 - 6th Annual Pharmaceutical Microbiology USA Conference - Cell therapies - Boston, MA
  • 27 April 2023 - Influenza mRNA Vaccines - lipid nanoparticle delivery - Online event
  • 2 - 4 May 2023 - 4th Gene Therapy Analytical Development Europe Summit - London, UK
  • 2 - 4 May 2023 - 2nd iPSC Manufacturing Summit - Gene Engineering - Boston, MA
  • 8 - 10 May 2023 - ISBioTech Nucleic Acids meeting - Production of DNA and RNA Biotherapeutics - Savannah, GA
  • 9 - 11 May 2023 - Novel Cell Line Engineering & Development Summit - ATMP focused - Boston, MA
  • 9 - 12 May 2023 - BioProcess International Europe - ATMP - Amsterdam, The Netherlands
  • 10 - 12 May 2023 - Bioprocessing Events 2023 - Berlin, Germany
  • 16 - 18 May 2023 - 2nd Next Generation RNA Therapeutics Summit - Boston, MA
  • 17 - 20 May 2023 - American Society of Gene and Cell Therapy (ASGCT) 26th Annual Meeting - Los Angeles, CA
  • 22 - 25 May 2023 - 5th Annual Allogeneic Cell Therapies Summit - Boston, MA
  • 23 - 24 May 2023 - Global Biologics Cell and Gene Legal Summit - Brussels, Belgium
  • 23 - 25 May 2023 - World Orphan Drug Congress USA 2023 - Washington, D.C.
  • 26 - 28 May 2023 - Symposium on World Cell and Molecular Biology 2023 - Singapore
  • 30 May - 1 June 2023 - 5th Treg Summit - Boston, MA
  • 31 May - 2 June 2023 - 2nd Cell Therapy Potency Assay Summit - Boston, MA
  • 6 - 8 June 2023 - Gene Therapy for Neurological Disorders Summit Europe - Amsterdam, The Netherlands
  • 7 - 8 June 2023 - Gene Therapy CMC & Analytics - Online event
  • 12 - 13 June 2023 - Annual meeting of the Netherlands Society of Gene & Cell Therapy - Lunteren, The Netherlands
  • 13 - 15 June 2023 - 3rd Gene Therapy Patient Engagement Summit - Boston, MA
  • 20 – 21 June 2023 - 3rd Gene and Cell Therapies: CMC, CGT & Vector Manufacturing Summit - Vienna, Austria
  • 21 – 22 June 2023 - 6th Aseptic Processing Summit - Manufacturing processes for ATMPs and vaccines - Vienna
  • 26 - 29 June 2023 - Gene Therapy & Rare Diseases conference - Boston, MA
  • 27 - 29 June 2023 - Next Generation Gene Therapy Vectors Summit - Boston, MA
  • 11 - 13 July 2023 - 4th RNA Editing Summit - Boston, MA
  • 26 - 28 July 2023 - 3rd Annual mRNA-Based Therapeutics Summit - Boston, MA
  • 9 August 2023 - Drug Discovery and Development - Cell & Gene Therapies - London, UK
  • 18 - 21 September 2023 - Cell & Gene Therapy Manufacturing & Commercialization US - Boston, MA
  • 18 - 21 September 2023 - BioProcess International - ATMP - Boston, MA
  • 27 - 29 September 2023 - Smart Bioprocessing & Pharma 4.0 Summit - Cell & Gene Therapies - Berlin, Germany
  • 24 – 27 October 2023 - Annual Congress of the European Society of Gene and Cell Therapy - Brussels, Belgium

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