New and Updated Clinical Gene Therapy Trials
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A Single Arm, Open, Exploratory Clinical Trial to Evaluate Efficacy and Safety for Combination Treatment of Replication Competent Adenovirus Double Suicide Gene Therapy and Radiation Therapy in Patients With Locally Advanced or Borderline Resectable Pancreatic Cancer
Feb 4, 2021 | 18:00 pmCondition: Pancreas CancerIntervention: Drug: Theragene armSponsors: Seoul National University Bundang Hospital; NewGenPharm IncoporationNot yet recruiting
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Gene Therapy for Chinese Hemophilia A
Jan 28, 2021 | 18:00 pmConditions: Hemophilia A; Gene TherapyIntervention: Genetic: Injection of GS001Sponsor: Institute of Hematology & Blood Diseases HospitalRecruiting
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An Exploration of the Impact of Gene Therapy on the Lives of People With Haemophilia and Their Families
Jan 26, 2021 | 18:00 pmCondition: HemophiliaIntervention: Other: Qualitative interviewSponsors: Haemnet; UniQure Biopharma B.V.Recruiting
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Study to Evaluate the Efficacy and Safety of PF-07055480 in Moderately Severe to Severe Hemophilia A Adults
Apr 30, 2020 | 18:00 pmCondition: Hemophilia AIntervention: Biological: Recombinant AAV2/6 Human Factor VIII Gene TherapySponsor: PfizerRecruiting
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AAV Gene Therapy Screening/Observational Protocol (ECLIPSE)
Feb 17, 2020 | 18:00 pmConditions: Hemophilia B; Blood Coagulation Disorders, Inherited; Blood Coagulation Disorder; Haematologic DiseaseIntervention: Sponsor: Freeline TherapeuticsRecruiting
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Gene Therapy for APOE4 Homozygote of Alzheimer's Disease
Aug 16, 2018 | 18:00 pmConditions: Alzheimer Disease; Early Onset Alzheimer DiseaseIntervention: Biological: AAVrh.10hPOE2 vectorSponsors: Weill Medical College of Cornell University; Alzheimer's Drug Discovery FoundationRecruiting
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Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency
Jul 26, 2018 | 18:00 pmCondition: Severe Combined Immunodeficiency, X-LinkedIntervention: Drug: Lentiviral vector transduced CD34+ cellsSponsor: Great Ormond Street Hospital for Children NHS Foundation TrustRecruiting
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Long-Term Follow-Up Gene Therapy Study for Achromatopsia CNGB3 and CNGA3
Sep 12, 2017 | 18:00 pmCondition: AchromatopsiaIntervention: Biological: either AAV - CNGB3 or AAV - CNGA3Sponsors: MeiraGTx UK II Ltd; Syne Qua Non Limited; EMAS PharmaRecruiting
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Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Mar 1, 2011 | 18:00 pmCondition: X-Linked Severe Combined Immune Deficiency (XSCID)Interventions: Drug: Palifermin; Drug: Busulfan; Biological: Ex vivo culture and transduction of the patient's autologous CD34+ HSC with lentivirus vector VSV-G pseudotyped CL20- 4i-EF1a-hyc-OPT vectorSponsor: National Institute of Allergy and Infectious Diseases (NIAID)Recruiting
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Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies
Mar 22, 2007 | 17:00 pmConditions: Prostate Cancer; Liver Cancer; Breast Cancer; Colon Cancer; Lung CancerIntervention: Sponsor: National Cancer Institute (NCI)Recruiting
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