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News: Gene Therapy Sector Needs Better Cell Lines for Vector Production

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Gene therapy developers targeting diseases requiring high dose therapies face a challenge. Current vector production cell lines and genetic manipulation techniques are too costly for large-scale manufacturing, according to new research. The study, by scientists at Portugal’s Instituto de Biologia Experimental e Tecnológica (iBET), looked at areas of gene therapy production where innovation is needed. 

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Conference: Next Generation RNA Therapeutics Summit

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Are you looking to solve challenges with current RNA therapeutics, such as the degradation of RNA by RNAses, the difficulty of RNA crossing the cell membrane by diffusion and the immunogenicity elicited by exogenous RNA?

Next generation RNA therapeutics can help! The Next Generation RNA Therapeutics Summit comes to Boston on May 24-26, 2022, to unite experts to discuss how novel modalities from self-replicating to circular RNAs have the potential to overcome key challenges faced by current generations.

Don’t miss your chance to hear from speakers from Pfizer, Moderna, Kernal Biologics, Replicate Bioscience, Orna Therapeutics, BioNTech and more at the only summit dedicated to successfully translating safe and effective next generation RNA therapeutics into the clinic.

Gene Therapy Net is also pleased to announce our exclusive discount code for your use. Save 10% on your pass to the summit with the code GTN10! 

Register now…

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Conference: Genetic Vaccine Development for Infectious Diseases Summit

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The 2nd Genetic Vaccine Development for Infectious Diseases Summit, May 24-26, 2022 in Boston is dedicated to Delivering the New Era of Vaccinology Through Optimizing the Clinical Translation, Discovery, & Manufacturing of RNA, DNA, & Viral Vector-Based Vaccines for Respiratory & Infectious Diseases Worldwide.

Join 150+ senior decision makers from pre-clinical and clinical development, infectious diseases, virology, and R&D from the world’s leading vaccine developers including Moderna, Pfizer, Sanofi and more while accessing three ground-breaking days of content across two streams, 12+ hours of networking, and a focus day dedication to respiratory infections.
Register now…

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Conference: ALS Drug Development Summit 

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Uniquely positioned to rapidly advance life-changing ALS therapeutics, the inaugural ALS Drug Development Summit (May 24-26, 2022) is the definitive industry forum for understanding promising targets for familial and sporadic disease, developing alternative outcome measures beyond ALSFRS-R, and enhancing innovative trial design.

Get the latest updates on the HEALEY ALS Platform Trial, predictive algorithms for managing inclusion criteria, and designing clinical trials for combination therapy with Cytokinetics, QurAlis, and Barrow Neurological Institute to drive innovation in trial design and assess more sensitive outcome measures

Register now…

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Conference: 3rd Annual Gene Therapy Analytical Development EU Summit 

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Join Gene Therapy Analytical Development Europe, 30 May – 1 June, 2022 in London, to uncover the robust analytical methods to guarantee safe, high quality, consistent and efficacious gene therapy products.

Whether you're looking for specific characterisation, potency, or infectivity approaches to improve your current analytical toolbox or if you're seeking to understand how gene therapy analytics differ from other biologics you've worked on in the past, this focused, technical event will provide insights specifically on the unique analytical challenges posed by gene therapy vectors, delivered by 'boots on the ground' scientists grappling with these challenges first-hand.

Join 150+ analytical pioneers to discover the realities of working with tools like dPCR, AUC and HPLC, as well as how and where these tools can be most effective in process development, and what the European regulators expect in order to grant approval. Whether you're working with AAV or lentiviral vectors, this is your opportunity to enhance your existing analytical methods and explore innovative new tools to support safe and effective gene therapy development.

Register now…

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Conference: 2nd Annual Gene Therapy Patient Engagement Summit

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Integrate the Patient Voice to Develop Safer and More Effective Gene Therapies That Are Meaningful to Patients. As investment in gene therapies continues to grow rapidly, more effectively engaging patients throughout development has become a priority for any company serious about building safer and more meaningful gene therapy programs.

In this context, the 2nd Annual Gene Therapy Patient Engagement Summit, June 7-9, 2022 in Boston, will unite patient advocacy and engagement leaders from gene therapy and gene editing drug developers, patient groups and patients themselves to address the specific challenges of genetic therapy patient engagement, generating actionable insights through detailed case studies and open, honest discussions.

Join us to hear directly from companies and institutions including Spark Therapeutics, Ultragenyx, FDA, Global Genes, and CRISPR Therapeutics on key topics including managing expectations across gene therapy development, navigating patient input on one-time transformative treatments with novel clinical trial designs combined with extensive follow-ups, and developing educational materials on gene therapy to raise awareness in collaboration with patient advocacy organizations. Leverage their knowledge and experiences to ultimately ensure effective creation and implementation of patient-centric gene therapy programs.

Register now…

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Conference: 9th Monolith Summer Symposium 

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BIA Separations, now part of Sartorius invites you to MSS2022, the 9th Monolith Summer Symposium which will take place online and in-person in Portoroz, Slovenia from June 13th to June 17th 2022.
Monolith Summer Symposium is a 5-day scientific symposium dedicated to the use of monolith chromatography in the field of gene therapy. Event is specifically designed for people working with gene therapy vectors, exosomes, vaccines, DNA and RNA, bacteriophages, large proteins, and other big biomolecules.

MSS2022 will follow a new format that introduces wet-lab workshops which will be coordinated with oral presentations. The event will continue to focus on the evolution of monolith technology, but an increased emphasis will also be placed on the applications of technology. Due to the unstable covid situation and travelling restrictions, you will be able to attend lectures also in virtual format.

Register now…

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Conference: Next Generation CAR & T Cell Therapies 2022

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Take steps to improve the safety and efficacy of novel CAR modalities through translational science and cutting-edge clinical data. Delve into topics that surround revolutionizing cell and gene engineering - groundbreaking autologous and allogeneic treatments for blood borne and solid tumors!

Registration is now open for our Next Generation CAR & T Cell Therapies hybrid event on June 14-16, 2022! To meet the preferences of our stay-at-home and travelling audience, you have the choice to join us either digitally or in-person at San Francisco, California.

Attend our event to revolutionize cell and gene engineering through ground-breaking autologous and allogenic treatments for blood borne and solid tumors! Register today to get a 10% discount by using the VIP Code “GeneTherapy10”!
Register now…

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Conference: 2nd Inner Ear Disorders Therapeutics Summit

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Biotech companies are paving the way to displace the cochlear implant and cater for the huge unmet need in hearing and balance disorders. The field is booming with excitement, with pharma companies increasing investment into these pipelines in the race to successfully reverse hearing damage. 

Returning as an in-person event to Boston, the 2nd Inner Ear Disorders Therapeutics Summit, June 20-23, 2022, will unite drug developers focusing on preventative and regenerative approaches targeting the inner ear. 

Debate the clinical applicability of different modalities, including small molecule, stem cell and gene therapy; accurately monitor hearing loss progress, successfully identify new targets, optimize preclinical models, discuss combination strategies for drugs and devices and hear the latest clinical updates and novel translatable research of the inner ear.
Register now…

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The UAE Government is heavily investing in precision medicine

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A unique chance to meet key acquisitions heads and policy makers who are driving personalised medicine in the Middle East; join us in May in Dubai. 
Register now…

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Life science investors are looking for the best health-tech ideas

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Meet top-end money teams — network with some of the most influential investors in the Middle East; join us in May in Dubai.
Register now…

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Upcoming conferences and meetings

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  • 18 – 20 April 2022 - 4th Neuroimmunology Drug Development Summit - Boston, MA
  • 19 – 21 April 2022, 2nd Gene Therapy Medical Affairs Summit, Boston, MA
  • 21 - 22 April 2022 - Global Bioprocessing Summit - ATMP Development - Berlin, Germany
  • 25 - 26 April 2022 - 9th Annual Conference Pre-Filled Syringes East Coast - Viral vector deliveries - Boston, MA
  • 25 - 27 April 2022 - 3rd Supply Chain and Logistics for Cell Therapies Summit, Boston, MA
  • 26 - 28 April 2022 - 5th Neoantigen Summit Europe - T-cell therapies - Amsterdam, the Netherlands
  • 2 – 6 May 2022 - PEGS Boston Summit - Gene Therapy R&D Analytics - Boston, MA
  • 9 – 12 May 2022 - 4th Allogeneic Cell Therapies Summit - Boston, MA
  • 11 - 12 May 2022 - SMi’s 4th Annual Conference Injectable Drug Delivery - Gene Therapies - London, UK
  • 11 – 13 May 2022 - Global Bioprocessing Summit Europe - Cell & Gene therapy analytics - Frankfurt, Germany
  • 16 - 19 May 2022 - American Society of Gene and Cell Therapy (ASGCT) 25th Annual Meeting - Washington, D.C.
  • 17 - 18 May 2022 - Advanced Therapies (ATMP) – Challenges for Routine Applications - Frankfurt am Main, Germany
  • 24 - 26 May 2022 - 2nd Genetic Vaccine Development for Infectious Diseases Summit - Boston, MA
  • 24 - 26 May 2022 - ALS Drug Development Summit - Gene & Cell Therapies - Boston, MA
  • 24 - 26 May 2022 - Next Generation RNA Therapeutics Summit - Boston, MA
  • 30 May - 1 June 2022 - 3rd Annual Gene Therapy Analytical Development Europe Summit 2022 - London, UK
  • 7 - 9 June 2022 - 2nd Annual Gene Therapy Patient Engagement Summit - Boston, MA
  • 13 - 17 June 2022 - 9th Monolith Summer Symposium, mRNA, Vaccines, Gene Therapy Vectors - Portoroz, Slovenia
  • 14 - 16 June 2022 - Next Generation CAR & T Cell Therapies 2022 event - San Francisco, CA
  • 20 - 23 June 2022 - 2nd Inner Ear Disorders Therapeutics Summit - Gene Therapies - Boston, MA
  • 22 - 23 June 2022 - Rare & Genetic Neurodegenerative Drug Development Summit - Gene Therapies - Boston, MA
  • 27 - 29 June 2022 - 3rd TCR-based Therapies for Solid Tumors Summit - Boston, MA
  • 29 - 30 June 2022 - Onco Cell Therapy Summit (OCTS) - Boston, MA
  • 11 - 13 July 2022 - 3rd Annual Gene Therapy for Neurological Disorders Europe - Paris, France
  • 11 - 13 July 2022 - World Orphan Drug Congress USA 2022 - Boston, MA
  • 12 - 14 July 2022 - In Vivo Engineering of Therapeutic Cells Summit - Boston, MA
  • 12 - 14 July 2022 - BCMA Targeted Therapies - CAR-modified T-cell therapy - Boston, MA
  • 18 - 20 July 2022 - 2nd Annual Next Generation Gene Therapy Vectors Summit - Boston, MA
  • 26 - 28 July 2022 - 3rd Gamma Delta T Therapies Summit - Boston, MA
  • 26 - 28 July 2022 - 2nd Annual mRNA-Based Therapeutics Summit - Boston, MA
  • 26 - 28 July 2022 - iPSC Manufacturing Summit - Gene and Cell therapies - Boston, MA
  • 19 - 23 September 2022 - 7th Annual CAR-TCR Summit - Boston, MA
  • 21 - 22 September 2022 - Oligonucleotide Therapeutics and Delivery 2022 - London, UK
  • 26 - 28 September 2022 - International Human Gene Therapy Conference - Melbourne, Australia
  • 11 – 14 October 2022 - XXIX Congress of the European Society of Gene and Cell Therapy (ESGCT) - Edinburgh, UK

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