News: Avrobio stops work on rare disease gene therapy after unexpected study results

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Avrobio, a Cambridge, Massachusetts-based gene therapy developer, will unexpectedly stop work on one of its most advanced treatments, citing disappointing results from a clinical trial that contrast with earlier, more promising findings. In a statement Tuesday, Avrobio said it would stop recruiting patients into a mid-stage study testing its gene therapy for Fabry disease, a rare inherited disorder, and deprioritize the research program. Monitoring will continue for the 14 Fabry patients who have received Avrobio's therapy so far. 

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Conference: Next Generation CAR-TCR Summit 

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Formerly CAR-TCR Europe, the Next Generation CAR-TCR Summit, 22-24th February, 2022, has evolved out of the increasing need for drug developers to stay ahead of the curve as stakeholders across oncology turn to next generation developments and innovations.

Key insights will be shared from Matterhorn Biosciences, Affini-T Therapeutics, Kiromic BioPharma, Antion Biosciences, Zelluna Immunotherapy, T-Kinfe Therapeutics, AffyImmune and many more at the only meeting dedicated to accelerating novel, new generation cell therapies that are safer, more effective and have meaningful impact in diseases beyond oncology.
Join your CAR-TCR community and network with 300+ leaders from large pharma, biotech, academia and regulatory boards to discover novel in-vivo delivery, innovations in gene, base & prime editing; novel discovery platforms, overcoming the hostile tumour microenvironment, improving persistence & durability for greater clinical outcomes and more!
Whether you are developing novel constructs, new clinical trial strategies or innovative manufacturing approaches for large scale production, this multi-tracked meeting can support your whole team and provide the tools to advance your own pipeline towards clinical and commercial success.

Register now…

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Conference: 5th Annual Gene Therapy for Rare Disorders

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As the gene therapy field strives to strike the balance between clinical efficacy and product safety in the context of mounting regulatory scrutiny, Gene Therapy for Rare Disorders, March 7-10, 2022, will provide in-depth insights from experts who know how to drive clinical progress, optimize manufacturing, and demonstrate the value of gene therapy products to regulators, payers, and patients.

Across four days, this meeting will unite 600+ leading experts in Boston from innovative biotechs, large pharma, academia, and key service provider companies, delivering actionable insights and valuable networking opportunities to accelerate gene therapy progress.

This is your comprehensive guide to define your commercial path forward.

Register now…

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Conference: Joint meeting with the AGCTS and ASSCR 

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We are thrilled to announce that The Australasian Society for Stem Cell Research (ASSCR) and the Australasian Gene and Cell Therapy Society (AGCTS) will come together to host a conference from 9th to 11th March, 2022 in Melbourne, where we will showcase the latest discoveries in stem cell science and gene therapy.

The From Stem Cells and Genes to Therapies conference will highlight how stem cells can be used to understand development, create disease models and discover new treatments. We will also explore the latest innovations in gene therapy spanning vector development to clinical applications. Combining powerful genetic technologies with strategies for cell replacement and progression of clinical trials will be addressed alongside ethical and regulatory implications.  

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Conference: 11th Spring Meeting ISBioTech

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Join us for this world renowned 11th Spring Meeting ISBioTech, March 14-16, 2022, on the development and production of viruses needed for vaccines, plus gene and cell therapies and exosomes. In addition, parallel programs will cover the development of cellular therapies, plus products developed with baculovirus technology. Our programs are focused on providing real data and detailed methods. You’ll discuss scalable technologies with the individuals and organizations you want to learn from. You’ll also participate in valuable and challenging discussions on the development and production of the industry’s most difficult applications!  You can attend any talk you choose from all 3 concurrent programs.

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Conference: Bioprocessing Summit Europe

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Europe’s fastest growing Bioprocessing meeting is returning to Barcelona on 22-24 March, 2022, with more content, ground breaking science and practical case studies than ever before.

This eight track conference covers the full spectrum of bioprocessing and modalities with dedicated sessions on upstream and downstream processing, cell and gene therapy CMC and manufacturing, and the latest developments in analytics, stability and formulation.

Along with a unique set of unpublished case studies and learnings, the Summit also features educational Short Courses, Interactive Breakout Sessions, and a comprehensive Exhibit Hall showcasing the latest technologies, solutions and services supporting the rapidly growing bioprocessing industry.

Register now…

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Upcoming conferences and meetings

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• 18 - 20 January 2022 - Allogeneic Cell Therapies Summit Europe - London, UK
• 25 - 27 January 2022 - 2nd Multi-Functional Cell Therapies Summit - Online event
• 25 - 27 January 2022 - 2nd TGF-β for Immuno-Oncology Drug Development Summit - Online event
• 26 - 27 January 2022 - 5th Antigen-Specific Immune Tolerance Summit - Cell therapy approaches - Online event
• 1 - 2 February 2022 - Formulation & Delivery US: Gene and Cell Therapies - San Diego, CA
• 9 - 10 February 2022 - RNA Therapeutics event - Online event
• 14 - 16 February 2022 - 4th Bacteriophage Therapy Summit - Online event
• 15 - 17 February 2022 - Genetic Vaccine Analytical Development Summit - Online event
• 22 - 24 February 2022 - Next Generation CAR-TCR Summit - London, UK
• 7 - 10 March 2022 - 5th Annual Gene Therapy for Rare Disorders - Boston, MA
• 9 - 11 March 2022, From Stem Cells and Genes to Therapies - Joint meeting with the AGCTS and ASSCR, Melbourne
• 14 - 16 March 2022 -11th Spring Meeting ISBioTech - Viral vectors and vaccines - Norfolk, Virginia
• 22 - 24 March 2022 - Bioprocessing Summit Europe - Barcelona, Spain
• 28 - 30 March 2022 - 10th Neurodegenerative Drug Development Summit - Boston, MA
• 28 - 30 March 2022 - Advancing Gene Therapy 2022 - Boston, MA
• 29 - 31 March 2022 - 3rd Gene Therapy for Blood Disorders Summit - Boston, MA
• 29 March - 1 April 2022 - 2nd Gene Therapy Comparability Summit - Boston, MA
• 6 – 8 April 2022 - Global Bioprocessing Summits - Cell & Gene therapy analytics - San Francisco, CA
• 4 – 7 April 2022 - 2nd Gene Therapy for Muscular Disorders Summit - Boston, MA
• 13 – 15 April 2022 - European Society of Gene and Cell Therapy (ESGCT) Spring School - Athens, Greece
• 18 – 20 April 2022 - 4th Neuroimmunology Drug Development Summit - Boston, MA
• 19 – 21 April 2022, 2nd Gene Therapy Medical Affairs Summit, Boston, MA
• 21 - 22 April 2022 - Global Bioprocessing Summit - ATMP Development - Berlin, Germany
• 25 - 27 April 2022 - 3rd Supply Chain and Logistics for Cell Therapies Summit, Boston, MA
• 9 – 12 May 2022 - 4th Allogeneic Cell Therapies Summit - Boston, MA
• 11 – 13 May 2022 - Global Bioprocessing Summit Europe - Cell & Gene therapy analytics - Frankfurt, Germany
• 16 - 19 May 2022 - American Society of Gene and Cell Therapy (ASGCT) 25th Annual Meeting - Washington, D.C.
• 17 - 18 May 2022 - Advanced Therapies (ATMP) – Challenges for Routine Applications - Frankfurt am Main, Germany
• 13 - 17 June 2022 - 9th Monolith Summer Symposium, mRNA, Vaccines, Gene Therapy Vectors - Portoroz, Slovenia
• 11 – 14 October 2022 - XXIX Congress of the European Society of Gene and Cell Therapy (ESGCT) - Edinburgh, UK

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